What a bound is
What O-notation does not say
Big-O is a statement about a limit. It does not say how fast, it does not say which is better, it does not say anything at all about any particular n, and it discards precisely the factor that usually decides the answer. Knowing exactly what it claims is the difference between using it and being misled by it.
The constant the notation drops
Six algorithms on this site are Θ(n log n) and their comparison counts differ by a factor of two. The class is what they have in common; the constant is what distinguishes them. It is measurable to three digits, it is the number that actually decides between them, and it is precisely the number the classification is designed to discard.
A limit is not a prediction
Measured from n = 64 to n = 4,096, this site's hybrid merge sort fits a linear class better than n log n. Measured out to n = 65,536, the ranking reverses. Nothing changed but the range — and this is not a flaw in the method, it is the method finding the exact place where measurement stops being able to help.